Formulasi Dan Evaluasi Sediaan Hair Tonic Ekstrak buah pare (Momordica charantia L.) Pada Pertumbuhan Rambut Kelinci
DOI:
https://doi.org/10.33143/jhtm.v9i2.4202Abstract
Penelitian ini bertujuan untuk mengetahui kandungan senyawa flavonoid dan saponin yang terdapat pada buah pare yang sangat bagus sebagai perangsang rambut. Penelitian dilakukan secara eksperimental. Sediaan hair tonic dibuat dengan menambahkan ekstrak buah pare dengan variasikosentrasi yaitu 5g (F1), 10g (F2), 15g (F3) dan sebagai blangko (F0). Pengujian terhadap sediaan hair tonicmeliputi uji organoleptic, uji homogenitas, uji pH, uji iritasi dan uji aktifitas pertumbuhan rambut. Sediaan hair tonic stabil dalam penyimpanan dan homogenitas, pH sediaan (5,7-6,4) dan tidak terdapat kemerahan atau bengkak dikulit pada saat pemakaian sediaan. Hasil dari pertumbuhan rambut yaitu 5,0mm (F1), 5,6mm (F2), 6,7mm (F3) dan 4,3mm (F0). Hasil tersebut diketahui bahwa semakin tinggi kosentrasi maka semakin tinggi pula tingkat aktivitas pertumbuhan pada rambut dan hair tonicdengan penambahan ekstrak buah pare (Momordica charantia L.) dengan konsentrasi 15% (F3) mempunyai aktivitas terbaik dalam pertumbuhan rambut kelinci.
Kata Kunci : rambut, kelinci, ekstrak etanol, buah pare
This study aims to determine the content of flavonoid and saponin compounds in bitter melon which is very good as a hair stimulant. The research was conducted experimentally. Hair tonic preparations were made by adding bitter melon extract with various concentrations, namely 5g (F1), 10g (F2), 15g (F3) and as blank (F0). Tests on hair tonic preparations include organoleptic test, homogeneity test, pH test, irritation test and hair growth activity test. The hair tonic preparation is stable in storage and homogeneity, the pH of the preparation is (5.7-6.4) and there is no redness or swelling of the skin when using the preparation. The results of hair growth are 5.0mm (F1), 5.6mm (F2), 6.7mm (F3) and 4.3mm (F0). The results showed that the higher the concentration, the higher the level of hair growth activity and hair tonic with the addition of bitter melon fruit extract (Momordica charantia L.) with a concentration of 15% (F3) had the best activity in rabbit hair growth.
Keywords: hair, rabbit, ethanol extract, bitter melon Reference: Books and Journals
References
Aini, Q. (2017). Uji Aktivitas Pertumbuhan Rambut Kelinci Jantan Dari Sediaan Hair Tonic Yang Mengandung Ekstrak Etanol Daun Mangkokan (Nothopanax
Scutellarium L.). JFL : Jurnal Farmasi Lampung, 6(2), 1–12. https://doi.org/10.37090/jfl.v6i2.16
Amelia, Y., Rostamailis, R., & Rosalina, L. (2017). Pemanfaatan Kecambah Tauge Untuk Mengatasi Kerontokan Rambut Wanita Berjilbab. E-Journal Home Economic and Tourism, 14(1), 1–14. http://ejournal.unp.ac.id/index.php/jhet/article/view/7211
Fathonah, S. (2019). Uji Aktivitas Antioksidan Ektrak Etanol 96% pada Ramuan Rumput Bambut (Lophaterum gracile B.), Buah Pare (Momordica charantia) dan Rimpang Kunyit Putih (Curcuma zedoaria B.) dengan Metode DPPH Serta Identifikasi Senyawa Aktifitasnya. http://etheses.uin-malang.ac.id/15182/1/13630088 .pdf
Jafar, G., Adiyati, I., & Kartanagara, F. F. (2017). Pengembangan Formula dan Karakterisasi Nanoemulsi Ekstrak Kombinasi Daun Teh dan Mangkokan Yang Diinkorporasikan ke dalam Spray Sebagai Penumbuh Rambut. Jurnal Pharmascience, 4(2), 155–166.
https://ppjp.ulm.ac.id/journal/index.php/pharmascience/article/view/5769/4832
Meilina, R., & Afriana, S. (2019). Efek Antiinflamsi Gel Kacang Hijau Pada Mencit Putih (Mus Musculus). Journal of Healthcare Technology and Medicine, 5(2), 231–238. https://jurnal.uui.ac.id/index.php/JHTM/article/view/422/167
Meilina, R. (2017). Efek Relaksasi Ekstrak Dan Fraksi Daun Belimbing Wuluh (Averrhoa Bilimbi L .) Terhadap Kontraksi Otot Polos Ileum Tikus Terisolasi Oleh : Rulia Meilina Program Studi Magister Farmasi Efek Relaksasi Ekstrak Dan Fraksi Daun Belimbing Wuluh ( Averrhoa bilim). https://repositori.usu.ac.id/bitstream/handle/123456789/715/157014024.pdf?sequen ce=1&isAllowed=y
Meilina, R., Dewy, R., & Izzzati, N. (2021). Sebagai Bahan Pembuatan Hand Sanitizer Education of the Utilization of Citrus Aurantifolia and. 3(1), 36–39. https://jurnal.uui.ac.id/index.php/jpkmk/article/view/1432
Meilina, R., Revina, D., & Nadia, P. (2020). Sosialisasi pemanfaatan tanaman obat keluarga (toga) untuk meningkatkan imun tubuh di masa pandemi covid-19. Jurnal Pengabdian Masyarakat (Kesehatan), 2(2), 89–94. https://jurnal.uui.ac.id/index.php/jpkmk/article/view/1141
Meilina, R., Nadya, Keusumawati, & Nuzul Raudhatun. (2021). Aktivitas Penyembuhan Luka Salep Ekstrak Biji Ketumbar (Coriandrum sativum L.) pada mencit (Mus musculus L.) yang terinfeksi Staphylococcus Aureus). Journal of Healtcare Technology and Medicine Vol. 7 No. 2.
https://jurnal.uui.ac.id/index.php/JHTM/article/view/1990
Meilina, R., Nufus N, Nurman S, & Ramadhani D. (2018). Formulasi Lotion Ekstrak Air Daun Tahi Ayam (Tageteserecta L.) sebagai Repellent Nyamuk. Journal of Healthcare Technology and Medicine Vol. 4 No. 1.
https://jurnal.uui.ac.id/index.php/JHTM/article/view/171
Rusdiana, I., & Maspiyah. (2018). Pengaruh Proporsi Ekstrak Lidah Buaya (Aloe Vera) Dan Madu Sebagai Bahan Aktif Hair Tonic. Universitas Negeri Surabaya, 07, 113–
https://ejournal.unesa.ac.id/index.php/jurnal-tata-rias/article/view/25020
Patel, S., Sharma, V., Chauhan, N. S., & Thakur, M. (2015). 004AR.pdf. Hair Growth: Focus on Herbal Therapeutic Agent Satish, 12, 21–42. https://pubmed.ncbi.nlm.nih.gov/26058803/
Downloads
Issue
Section
License
I. ORIGINALITY, AUTHORSHIP, AND COPYRIGHT
The manuscripts submitted for publication must be research works written in English that have not been previously published and  are not being considered for publication elsewhere. All the authors must have agreed to the submission and to the order of their names on the title page. They must also have agreed that the corresponding author may act on their behalf throughout the editorial review and publication process. The corresponding author is responsible for obtaining such agreement.
Requests for changes in authorship (order of listing or addition or deletion of names) after submission should be accompanied by signed statements of agreement from all the parties involved. To maintain and protect the publisher‘s ownership and rights and to protect the original authors from misappropriations of their published work, author(s) are required to sign a Journal Publishing Agreement and send it to the editorial office (jhtm@uui.ac.id).
II. PERMISSION
The author is responsible for acquiring the permission(s) to reproduce any copyrighted figures, tables, data, or text that are being used in the submitted paper. Authors should note that text quotations of more than 250 words from a published or copyrighted work will require grant of permission from the original publisher to reprint. The written permission letter(s) must be submitted together with the manuscript.
III. EDITORIAL REVIEW AND REVISION
All papers will be critically read by at least two anonymous reviewers, selected for their competence in the subject area of the paper. Acceptance of the paper will depend upon its scientific merit and suitability for the journal. A paper may be accepted in its original form or subject to revision.
The reviewers' (and editor's) suggestions will be conveyed to the author, who will then have an opportunity to revise the paper. A manuscript returned to an author for revision can be held for a maximum of eight weeks.
The accepted paper will be edited by native English speakers. The cost of language editing service is currently free.
IV. PROOFS
Galley proofs (PDF format) for an accepted article will be sent by e-mail to the corresponding author for copyediting corrections. The core content of an article cannot be changed at this time. It is the author's responsibility to check the entire manuscript, including tables, figure legends, and cited reference numbers, not just the items queried. The proofs should be corrected and mailed to the editorial office within 48 hours of receipt in order to expedite publication. Only one set of corrections will be accepted. In other words, it is important to ensure that all of your corrections are sent to us in one communication.
V. Â REPRINTS
Five free reprint copies of the published article will be shipped to the corresponding authors in Indonesia only, approximately two weeks after the issue is printed. Authors, including overseas authors, who wish to purchase reprints, are required to complete the Reprint Order Form, which will be sent with the galley proofs to corresponding authors. This form must be returned together with the corrected galley proofs.
