Korelasi Paparan Benzene Dengan Gambaran Jenis Hitung Leukosit Pada Karyawan SPBU X Dan Y
DOI:
https://doi.org/10.33143/jhtm.v6i2.1138Abstract
Abstrak
Benzene (C6H6) merupakan salah satu kandungan produk migas bensin yang berfungsi untuk meningkatkan nilai oktan. Paparan benzene secara kronis dapat menyebabkan penurunan produksi sel-sel darah di sumsum tulang. Penelitian ini bertujuan untuk melihat korelasi paparan benzene melalui pemeriksaan kadar ttMA (trans, trans-Muconic Acid) dalam urin dengan gambaran jenis hitung leukosit pada karyawan di Stasiun Pengisian Bahan Bakar Umum X dan Y Medan. Penelitian ini merupakan suatu penelitian deskriptif analitik dengan desain cross sectional study. Responden penelitian ini adalah karyawan beberapa SPBU di Medan (n=43) dengan masa kerja ≥ 6 bulan. Hasil penelitian menunjukkan bahwa 9 dari 43 responden memiliki kadar ttMA lebih dari 500 µg/g creatinin. Korelasi kadar ttMA dengan jenia hitung leukosit tidak signifikan (p>0,05), ttMA berkorelasi negatif dengan jenis hitung leukosit. Kesimpulan penelitian ini adalah bahwa perbedaan rata-rata kadar ttMA pada masa kerja ≤ 1 tahun dan masa kerja > 1 tahun tidak signifikan (p=0,45), dan perbedaan rata-rata kadar ttMA pada subjek yang merokok dan tidak merokok tidak signifikan (p=0,559).
Kata Kunci: benzene, ttMa, leukosit
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