SKRINING FITOKIMIA DAUN KEMANGI (Ocimum Sanctum L.) SEBAGAI DASAR MUTU BAHAN BAKU FARMASI

Authors

  • Winda Kesuma Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Alwashliyah Medan
  • Minda Sari Lubis Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Alwashliyah Medan
  • Anny Sartika Daulay
  • Rafita Yuniarti

DOI:

https://doi.org/10.33143/jhtm.v12i1.5682

Keywords:

Simplisia kemangi, Skrining fitokimia, Metabolit sekunder, Mutu bahan baku

Abstract

Daun kemangi (Ocimum sanctum L.,) memiliki potensi sebagai bahan baku farmasi berbasis bahan alam sehingga perlu pengkajian mutu awal. Tujuan penelitian ini mengidentifikasi karakteristik simplisia dan golongan metabolit sekunder daun kemangi melalui pemeriksaan organoleptik, makroskopik, parameter fisiko kimia, seerta skrining fitokimia kualitatif. Hasil menunjukkan simplisia memiliki karakteristik yang konsisten, memenuhi persyaratan mutu, dan mengandung alkaloid, flavonoid, saponin, fenol, glikosida dan steroid yang berpotensi sebagai bahan baku herbal di bidang farmasi dan kesehatan.

Author Biographies

  • Winda Kesuma, Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Alwashliyah Medan
    Lecturer in Pharmacy, Faculty of Pharmacy, Universitas Muslim Nusantara Medan with research interests in phytochemistry
  • Minda Sari Lubis, Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Alwashliyah Medan
    Undergraduate student in Pharmacy with research interests in phytochemistry

References

Apmarja, S. U., Nasution, M. A., Nasution, H. M., & Yuniarti, R. (2025). Penetapan kadar flavonoid total dan aktivitas antioksidan ekstrak etanol, fraksi n-heksan, etil asetat daun senggani (Melastoma candidum D.Don) secara spektrofotometri visibel. Journal of Pharmaceutical and Sciences, 420–436. https://doi.org/10.36490/journal-jps.com.v8i1.797

Ariani, N., Febrianti, D. R., & Niah, R. (2020). Uji aktivitas ekstrak etanolik daun kemangi (Ocimum sanctum L.) terhadap Staphylococcus aureus secara in vitro. Jurnal Pharmascience, 7(1), 107. https://doi.org/10.20527/jps.v7i1.8080

Devina Chandra, Tampubolon, M. I., & Priltius, N. (2023). Formulasi dan pengujian sediaan deodorant spray yang mengandung ekstrak daun kemangi (Ocimum basilicum L.) terhadap bakteri Staphylococcus aureus. Jurnal Siti Rufaidah, 1(4), 17–25. https://doi.org/10.57214/jasira.v1i4.37

Direktur Jenderal Pengawasan Obat dan Makanan. (1989). Materia Medica Indonesia (Edisi V). Jakarta: Departemen Kesehatan Republik Indonesia.

Fitri, R. M., Lubis, M. S., Dalimunthe, G. I., & Yuniarti, R. (2023). Skrining fitokimia, formulasi dan uji mutu fisik nanoserum ekstrak bonggol nanas (Ananas comosus (L.) Merr). Journal of Pharmaceutical and Sciences, 6(3), 1346–1355. https://doi.org/10.36490/journal-jps.com.v6i3.207

Gurning, K., & Simanjuntak, H. A. (2020). Karakterisasi dan skrining fitokimia daun pirdot (Saurauia vulcani Korth.). Eksakta: Jurnal Penelitian dan Pembelajaran MIPA, 5(2), 98–105. https://doi.org/10.31604/eksakta.v5i2.98-105

Krismayadi, K., Halimatushadyah, E., Apriani, D., & Cahyani, M. F. (2024). Standarisasi mutu simplisia dan ekstrak etanol daun kemangi (Ocimum x africanum Lour.). Pharmacy Genius, 3(2), 67–81. https://doi.org/10.56359/pharmgen.v3i2.333

Marsila, R., Febrianti, A., Sari, A. V., Fetrilia, Afifah, S. N., Naurah, N. T., Mardiana, & Wahab, S. (2025). Ekstraksi dan identifikasi senyawa bioaktif ekstrak daun kemangi (Ocimum basilicum L.). Jurnal Lentera Ilmiah Kesehatan, 3(1), 1–8. https://doi.org/10.52120/jlik.v3i1.59

Muldianah, D., Nurdimayanthi, D. A., Rahmawati, D. S., & Fadhilah, H. (2021). Teknik isolasi dan identifikasi senyawa glikosida dari berbagai tanaman. PharmaCine: Journal of Pharmacy, Medical and Health Science, 2(1), 11–21. https://doi.org/10.35706/pc.v2i1.5577

Noer, S., Pratiwi, R. D., & Gresinta, E. (2018). Penetapan kadar senyawa fitokimia (tanin, saponin dan flavonoid) sebagai kuersetin pada ekstrak daun inggu (Ruta angustifolia L.). Jurnal Eksakta, 18(1), 19–29. https://doi.org/10.20885/eksakta.vol18.iss1.art3

Novia, D. (2020). Skrining fitokimia ekstrak etanol daun jati dan infusa daun jati (Tectona grandis L.S) dengan metode kromatografi lapis tipis (KLT). Jurnal Ilmiah Pharmacy, 7(2), 159–174. https://doi.org/10.52161/jiphar.v7i2.188

Nuraida, N., Ridwanto, R., Daulay, A. S., & Nasution, H. M. (2024). Penentuan kadar flavonoid total ekstrak etanol kayu kuning (Arcangelisia flava (L.) Merr.) dan uji antibakteri Staphylococcus aureus. Journal of Pharmaceutical and Sciences, 411–421. https://doi.org/10.36490/journal-jps.com.v7i3.598

Nuryana, P., Subaidah, W. A., & Hidayati, A. R. (2023). Formulasi tablet hisap ekstrak etanol daun kemangi (Ocimum sanctum L.) dengan variasi konsentrasi bahan pengikat gelatin. Sasambo Journal of Pharmacy, 4(1), 53–62. https://doi.org/10.29303/sjp.v4i1.213

Parapat, A. R. B., Ridwanto, R., Yuniarti, R., & Rani, Z. (2025). Uji aktivitas antioksidan ekstrak dan fraksinasi daun tekelan (Chromolaena odorata (L.) R.M.King & H.Rob) serta uji antibakteri terhadap Staphylococcus aureus dan Escherichia coli. Journal of Pharmaceutical and Sciences, 2560–2574. https://doi.org/10.36490/journal-jps.com.v8i4.1059

Rinto, R., Sudirman, S., Ulqodry, T. Z., Pitayati, P. A., & Balqis, F. R. (2024). Efektivitas daun kemangi sebagai anti lalat pada pembuatan ikan asin sepat rawa (Trichopodus trichopterus). Jurnal Pengolahan Hasil Perikanan Indonesia, 27(5), 351–361. https://doi.org/10.17844/jphpi.v27i5.50005

Rohenti, I. R. (2023). Uji aktivitas ekstrak etanol 70% daun alpukat (Persea americana Mill.) terhadap penurunan kadar glukosa darah pada mencit jantan (Mus musculus L.). Jurnal Sabdariffarma, 10(2), 21–33. https://doi.org/10.53675/jsfar.v10i2.985

Siagian, A. Y., Yuniarti, R., Daulay, A. S., & Pulungan, A. F. (2025). Kandungan vitamin C dan uji aktivitas antioksidan teh herbal kombucha daun bidara (Ziziphus mauritiana Lam). Journal of Pharmaceutical and Sciences, 1004–1017. https://doi.org/10.36490/journal-jps.com.v8i2.880

Siregar, M., Lubis, M. S., Yuniarti, R., & Rani, Z. (2025). Formulasi, evaluasi dan aktivitas antioksidan sabun padat serbuk nano teh celup bekas. Journal of Pharmaceutical and Sciences, 2641–2661. https://doi.org/10.36490/journal-jps.com.v8i4.1055

Zahira Ahmad, M., Lubis, M. S., Dalimunthe, G. I., & Rani, Z. (2025). Formulasi dan karakteristik fisik krim nano ekstrak bonggol nanas (Ananas comosus (L.) Merr) sebagai anti-aging. Jurnal Ilmiah Manusia dan Kesehatan, 8(1), 241–251. https://doi.org/10.31850/makes.v8i1.3505

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Published

2026-03-01

Issue

Vol. 12 No. 1 (2026): APRIL 2026

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