FORMULASI dan UJI AKTIVITAS SEDIAAN KRIM EKSTRAK BIJI ALPUKAT (Persea americana Mill.) SEBAGAI PENYEMBUHAN LUKA BAKAR PADA TIKUS PUTIH JANTAN (Rattus norvegicus)
DOI:
https://doi.org/10.33143/jhtm.v11i2.5705Abstract
Luka bakar merupakan kerusakan jaringan kulit akibat trauma panas. Biji alpukat (Persea americana Mill.) mengandung flavonoid yang bersifat antiinflamasi, antioksidan, dan berperan dalam penyembuhan luka. Penelitian ini bertujuan mengetahui efektivitas ekstrak biji alpukat serta formula krim yang optimal untuk pengobatan luka bakar. Pengujian dilakukan pada tikus jantan dengan empat formula: F0 (kontrol), F1 (5%), F2 (10%), dan F3 (15%). Hasil menunjukkan seluruh krim memenuhi standar SNI dan mempercepat penyembuhan luka bakar, dengan aktivitas terbaik pada formula F3 (15%). Kata kunci: Krim, Luka Bakar, Biji Alpukat.
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